BrenneckeLab

2014

  1. The exon junction complex is required for definition and excision of neighboring introns in Drosophila.

    Hayashi R, Handler D, Ish-Horowicz D,Brennecke J
    Genes Dev. 2014 Aug 15;28(16):1772-85. doi: 10.1101/gad.245738.114.

  2. The rhino-deadlock-cutoff complex licenses noncanonical transcription of dual-strand piRNA clusters in Drosophila.

    Mohn F, Sienski G, Handler D, Brennecke J
    Cell. 2014 Jun 5;157(6):1364-79. doi: 10.1016/j.cell.2014.04.031.

2013

  1. Drosophila Gtsf1 is an essential component of the Piwi mediated transcriptional silencing complex

    Donertas D, Sienski G, Brennecke J
    Genes Dev. 2013 Aug 1;27(15):1693-705.

  2. The Genetic Makeup of the Drosophila piRNA Pathway.

    Handler D, Meixner K, Pizka M, Lauss K, Schmied C, Gruber FS, Brennecke J.
    Mol Cell. 2013 Jun 6;50(5):762-77.

2012

  1. Transcriptional Silencing of Transposons by Piwi and Maelstrom and Its Impact on Chromatin State and Gene Expression.

    Sienski G, Donertas D, Brennecke J.
    Cell. 2012 Nov 21;151(5):964-80

  2. The Cochaperone Shutdown Defines a Group of Biogenesis Factors Essential for All piRNA Populations in Drosophila.

    Olivieri D, Senti KA, Subramanian S, Sachidanandam R, Brennecke J.
    Mol Cell. 2012 Sep 28;47(6):954-69

2011

  1. A systematic analysis of Drosophila TUDOR domain-containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors.

    Handler D, Olivieri D, Novatchkova M, Gruber FS, Meixner K, Mechtler K, Stark A, Sachidanandam R, Brennecke J.
    EMBO J. 2011 Aug 23;30(19):3977-93

  2. A genome-scale shRNA resource for transgenic RNAi in Drosophila.

    Ni JQ, Zhou R, Czech B, Liu LP, Holderbaum L, Yang-Zhou D, Shim HS, Tao R, Handler D, Karpowicz P, Binari R, Booker M, Brennecke J, Perkins LA, Hannon GJ, Perrimon N.
    Nat Methods. 2011 May;8(5):405-7.

2010

  1. The piRNA pathway: a fly's perspective on the guardian of the genome.

    Senti KA, Brennecke J.
    Trends Genet. 2010 Dec;26(12):499-509.

  2. An in vivo RNAi assay identifies major genetic and cellular requirements for primary piRNA biogenesis in Drosophila.

    Olivieri D, Sykora MM, Sachidanandam R, Mechtler K, Brennecke J.
    EMBO J. 2010 Oct 6;29(19):3301-17.